Science has the potential to make extraordinary leaps when the right people, ideas, and technology come together to solve complex problems. 

We’re disrupting the traditional research space by re-imagining how science is done and funded, with a focus on supporting both projects and people. Through thoughtful and nimble investments of time and resources into the most pressing scientific questions, we develop tailored solutions and encourage bold, relentless scientific exploration toward our goals.

Single Ventricle Heart Disease

Our biomedical research work focuses on a rare form of congenital heart defects called single ventricle heart disease. While this field is in its infancy, with limited knowledge of cause, risk, outcomes, or treatments, we are confident that through coordinated strategic and interdisciplinary work, dynamic teaming, and flexible funding, we can illuminate a functional cure for patients and their families.

Research Roadmap

Developed collaboratively with scientific leaders in the community, the single ventricle Research Roadmap is a living ten-year plan toward comprehensive, multidisciplinary, and programmatic solutions to understand and overcome single ventricle heart disease.

Comprised of five significant knowledge and infrastructure gaps slowing down progress in single ventricle research, the roadmap defines crucial research pathways for exploration and investment.

Learn more

Single Ventricle Scientific Advisory Board

Deepak Srivastava, MD
Deepak Srivastava, MD

President, Gladstone Institutes

Professor, University of California, San Francisco

David Rosenthal, MD
David Rosenthal, MD

Professor, Pediatric Cardiology

Director, Pediatric Heart Failure and Transplantation

Stanford University School of Medicine and Lucile Salter Packard Children’s Hospital

Anthony Philippakis, M.D., Ph.D.
Anthony Philippakis, M.D., Ph.D.

Chief Data Officer, Institute Scientist

Broad Institute of MIT and Harvard

Jane Newburger, MD
Jane Newburger, MD

Commonwealth Professor of Pediatrics, Harvard Medical School

Associate Cardiologist in Chief for Academic Affairs, Boston Children’s Hospital

Alison Marsden, PhD
Alison Marsden, PhD

Professor of Pediatrics – Cardiology and Bioengineering

Stanford University 

Tain-Yen (T-Y) Hsia, MD
Tain-Yen (T-Y) Hsia, MD

Professor of Surgery, University College London

Professor of Surgery, University of Central Florida

Pediatric Cardiac Surgeon, Arnold Palmer Hospital for Children

Anthony B. Firulli, PhD
Anthony B. Firulli, PhD

Endowed Professor of Pediatrics

Indiana University School of Medicine

Rachael Cordina, MD, PhD
Rachael Cordina, MD, PhD

Clinical Academic Cardiologist, University of Sydney and Royal Prince Alfred Hospital

Clinical Senior Lecturer, University of Sydney

Christopher K. Breuer, MD
Christopher K. Breuer, MD

Director of the Center for Regenerative Medicine and Endowed Chair in Surgical Research, Nationwide Children’s Hospital

Director of Tissue Engineering, The Ohio State University

Patient and Family Advisory Board

Bulent Arman Aksoy, PhD
Bulent Arman Aksoy, PhD

Father to a Single Ventricle Daughter

Computational Biologist

Taylor Houlihan
Taylor Houlihan

Single Ventricle Fontan Patient

3rd Year Medical Student

Tawanna Nishibayashi, CPC
Tawanna Nishibayashi, CPC

Mother to a Post-Heart Transplant Single Ventricle Daughter

Owner/Lead DEI Consultant, Race Equity Solutions

Podcast Creator/Host, Broken Open