Finding a functional cure is central to solving single ventricle heart disease, but no one scientist, lab, or even field can do it alone.

Additional Ventures’ Cures Collaborative (AVCC) is a multidisciplinary team of nine investigators across eight institutions brought together to develop a regenerative medicine solution that can improve cardiac function and reduce poor outcomes.

A Multidisciplinary, Collaborative Approach

We’re fostering outstanding and accelerated science by bringing together a diverse team of investigators with complementary expertise and resources across basic, translational, and engineering sciences in concert with medical knowledge — all united by a common goal.

 

Scientific Goals

Together, team members determine overall research direction, developing group and individual research plans every six months as projects advance and discoveries are made.

The inaugural AVCC is focused on tissue engineering approaches that create cardiac function with a better risk-benefit profile than is currently achieved, for both the post-natal and Fontan population.

Cures Collaborative Members

The inaugural AVCC is composed of nine investigators, with leadership support from Additional Ventures and administrative support through University of Central Florida. The Cures Collaborative Co-Directors Dr. Chris Breuer and Dr. Tain-Yen Hsia provide organizational and strategic support. 

Over the next five years, the team will work together with the members of their labs to accelerate the pace of science using an integrated approach that tackles the problem from all sides. 

Tain-Yen Hsia, MD (Coordinator)
Tain-Yen Hsia, MD (Coordinator)

Pediatric Cardiothoracic Surgeon and Professor of Surgery

Arnold Palmer Hospital for Children and University of Central Florida

Chris Breuer, MD (Co-Coordinator)
Chris Breuer, MD (Co-Coordinator)

Director, Center for Regenerative Medicine

Nationwide Children’s Hospital

Stacey Rentschler, MD, PhD
Stacey Rentschler, MD, PhD

Associate Professor of Medicine, Cardiovascular Division

Washington University in St. Louis

Michael Davis, PhD
Michael Davis, PhD

Professor and Associate Chair of Biomedical Engineering, Director, Children’s Heart Research and Outcomes Center

Emory University and Georgia Tech

Mark Skylar Scott, PhD
Mark Skylar Scott, PhD

Assistant Professor of Bioengineering

Stanford University

Alison Marsden, PhD
Alison Marsden, PhD

Professor, Departments of Pediatrics and Bioengineering, and by courtesy, Mechanical Engineering

Stanford University

Adam Feinberg, PhD
Adam Feinberg, PhD

Professor, Department of Biomedical Engineering, Department of Materials Science & Engineering

Carnegie Mellon University

Jay Humphrey, PhD
Jay Humphrey, PhD

John C. Malone Professor of Biomedical Engineering and Department Chair

Yale University (School of Engineering and Applied Science, School of Medicine)