Biomedical Research

Announcing the Launch of the AHA/AV Collaborative Sciences Awards

September 7, 2023

We are thrilled to announce the launch of our newest awards program in single ventricle!

Together, the American Heart Association (AHA) and Additional Ventures (AV) have established the AHA/AV Collaborative Sciences Awards in Single Ventricle Heart Disease (CSAs) to support multidisciplinary, multi-institutional research teams addressing underlying biological mechanisms and clinical science related to complications and comorbidities of single ventricle heart disease.

This new research award program seeks to establish a multidisciplinary network of five teams who are enthusiastic about working transparently in a highly collaborative network – a team of teams sharing related, yet unique scientific goals, who prioritize innovation over safe bets, and who are willing to risk testing unconventional ideas. We encourage a forward-thinking approach to research that is not constrained by long-held hypotheses and dogma, and that is conducted in an environment of trust.

The CSAs are focused on the underlying biological mechanisms and clinical science related to complications and comorbidities of single ventricle heart disease and the post-Fontan condition to improve the lives of patients. Teams should focus their research efforts and scope on one or more of the following, in the context of single ventricle:

  • Fontan-Associated Liver Disease
  • Protein Losing Enteropathy and/or Lymphatic Perturbations
  • Ventricular Failure and/or Arrhythmias
  • Renal Failure
  • Mental Health and/or Neurocognitive Delay
  • Exercise Intolerance
  • Factors Leading to Resilience (i.e., super-Fontans)

In addition to generous research funds of $2.25M over three (3) years, the CSAs provide dedicated project management support for granted teams, as well as community development support through all-expense-paid biannual meetings and other networking opportunities that will set our teams up for success. We anticipate funding five AHA/AV Collaborative Sciences Awards, for approximately $13.2M in total costs for our collective investment.

Pre-Proposals (LOIs) are due by December 19.

Learn more and apply