Biomedical Research

The Role of Nonprofits in Solving Single Ventricle

July 11, 2022

Single ventricle is a burgeoning and exiting field, with opportunities that make it uniquely positioned for creative mechanisms of support.  Our team is thrilled to have contributed an editorial on single ventricle as part of the Journal of Cardiovascular Development and Disease Special Issue “Hypoplastic Left Heart Syndrome: Etiology, Pathogenesis, Management and The Future.”  Here, we outline our shared perspective that single ventricle is a solvable problem, and one that can be addressed by organizations who are committed to achieving curative solutions.

Traditional funding approaches often require large patient cohorts, a short time horizon for returns, and a foundation of disease knowledge that allow multiple targets to be tested – which is severely limiting for fields like single ventricle.  Thus, we believe a new approach to funding methodology and deployment, particularly one guided by nonprofits, is critical to address the unmet needs of this community and to drive rapid progress towards curative solutions.

To read more about the landscape of single ventricle, including areas of opportunity like interdisciplinary collaboration, community involvement, and infrastructure development, as well as the critical role of nonprofits in driving innovation and curative solutions, check out our article: Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease’.